|
gptkbp:instanceOf
|
gptkb:protein
membrane channel protein
|
|
gptkbp:alternativeName
|
CHIP28
water channel protein 1
|
|
gptkbp:associatedWith
|
gptkb:congenital_cataract
gptkb:nephrogenic_diabetes_insipidus
pulmonary edema
|
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gptkbp:discoveredBy
|
gptkb:Peter_Agre
|
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gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
eye
red blood cells
choroid plexus
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gptkbp:firstDescribed
|
1992
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gptkbp:foundIn
|
gptkb:human
gptkb:mouse
right
|
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gptkbp:function
|
water transport
facilitated diffusion of water
|
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gptkbp:gene
|
AQP1
|
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gptkbp:HGNC_ID
|
633
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Aquaporin-1
|
|
gptkbp:inhibitedBy
|
mercury compounds
|
|
gptkbp:locatedIn
|
gptkb:cell_membrane
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_7
gptkb:7p14
|
|
gptkbp:molecularWeight
|
28 kDa
|
|
gptkbp:Nobel_Prize_related
|
Peter Agre (2003 Nobel Prize in Chemistry)
|
|
gptkbp:not_permeable_to
|
gptkb:protons
ions
|
|
gptkbp:OMIM
|
107270
|
|
gptkbp:PDB
|
1J4N
|
|
gptkbp:structure
|
tetramer
six transmembrane domains
|
|
gptkbp:transportation
|
gptkb:water
glycerol (very low permeability)
|
|
gptkbp:UniProtID
|
P29972
|
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gptkbp:bfsParent
|
gptkb:Membrane_Channels
|
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gptkbp:bfsLayer
|
7
|