|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
Sirtuin 7
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:metabolic_syndrome
aging
cardiac hypertrophy
|
|
gptkbp:Entrez_Gene_ID
|
67609
ENSMUSP00000022500
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
gptkb:testis
heart
liver
|
|
gptkbp:family
|
sirtuin family
|
|
gptkbp:function
|
NAD+-dependent deacetylase
|
|
gptkbp:gene
|
Sirt7
Sirt7 gene
|
|
gptkbp:GO_term
|
gptkb:GO:0006355_(regulation_of_transcription,_DNA-templated)
GO:0003677 (DNA binding)
GO:0004407 (histone deacetylase activity)
GO:0005730 (nucleolus)
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
mouse Sirt7
|
|
gptkbp:interactsWith
|
gptkb:RNA_polymerase_I
gptkb:histone_H3
U3 snoRNA
|
|
gptkbp:involves
|
cellular stress response
chromatin remodeling
ribosomal RNA transcription
|
|
gptkbp:length
|
400
|
|
gptkbp:locatedOnChromosome
|
chromosome 11
|
|
gptkbp:location
|
nucleolus
|
|
gptkbp:molecularWeight
|
44 kDa
|
|
gptkbp:organism
|
gptkb:Mus_musculus
|
|
gptkbp:orthologIn
|
human SIRT7
|
|
gptkbp:postTranslationalModification
|
phosphorylation
sumoylation
acetylation
|
|
gptkbp:proteinFamily
|
gptkb:enzyme
|
|
gptkbp:regulates
|
cell proliferation
ribosome biogenesis
rDNA transcription
metabolic homeostasis
histone H3K18 acetylation
|
|
gptkbp:sequence_available_at
|
gptkb:NCBI
gptkb:UniProt
gptkb:Ensembl
|
|
gptkbp:UniProtID
|
Q9CZY3
|
|
gptkbp:bfsParent
|
gptkb:SIRT7
|
|
gptkbp:bfsLayer
|
8
|