Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
gptkb:Cytotoxic_T-lymphocyte-associated_protein_4
Cd152 |
| gptkbp:encodes |
gptkb:CTLA-4_protein
|
| gptkbp:Entrez_Gene_ID |
12477
ENSMUSG00000030803 |
| gptkbp:expressedIn |
activated T cells
|
| gptkbp:function |
negative regulator of T cell activation
|
| gptkbp:geneType |
protein-coding
|
| https://www.w3.org/2000/01/rdf-schema#label |
mouse Ctla4
|
| gptkbp:locatedOnChromosome |
chromosome 1
|
| gptkbp:mutationAssociatedWith |
autoimmunity
lymphoproliferative disorder |
| gptkbp:organism |
gptkb:Mus_musculus
|
| gptkbp:orthologIn |
human CTLA4
|
| gptkbp:pathway |
immune checkpoint pathway
|
| gptkbp:proteinFamily |
gptkb:immunoglobulin_superfamily
|
| gptkbp:regulates |
T cell proliferation
immune tolerance |
| gptkbp:relatedTo |
immune response
|
| gptkbp:UniProtID |
P09793
|
| gptkbp:bfsParent |
gptkb:CTLA4_gene
|
| gptkbp:bfsLayer |
7
|