mitomycin

URI: https://gptkb.org/entity/mitomycin
GPTKB entity
Statements (41)
Predicate Object
gptkbp:instanceOf gptkb:antibiotic
antineoplastic agent
gptkbp:administeredBy topical application
intravenous injection
gptkbp:ATCCode L01DC03
gptkbp:brand gptkb:Mitozytrex
gptkb:Mutamycin
gptkbp:CASNumber 50-07-7
gptkbp:category antineoplastic agent
antitumor antibiotic
gptkbp:discoveredBy Kazuo Wakabayashi
gptkbp:discoveredIn 1956
gptkbp:eliminatedIn renal
gptkbp:eliminationHalfLife 17-50 minutes
gptkbp:hasMolecularFormula C15H18N4O5
https://www.w3.org/2000/01/rdf-schema#label mitomycin
gptkbp:IUPACName (1aS,8S,8aR,8bS)-6-amino-8a-methoxy-5-methyl-1,1a,2,8,8a,8b-hexahydroazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7,9(6H)-trione
gptkbp:KEGGID D00455
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction DNA crosslinking
gptkbp:MeSH_ID D008937
gptkbp:metabolism liver
gptkbp:molecularWeight 334.33 g/mol
gptkbp:pregnancyCategory D (US)
gptkbp:producedBy gptkb:Streptomyces_caespitosus
gptkbp:PubChem_CID gptkb:CHEMBL1405
5746
DB00305
5543
gptkbp:sideEffect gptkb:hemolytic_uremic_syndrome
nausea
vomiting
myelosuppression
gptkbp:synonym gptkb:mitomycin_C
gptkbp:UNII UAN7V32PQD
gptkbp:usedFor gptkb:cancer
pancreatic cancer
bladder cancer
gastric cancer
gptkbp:bfsParent gptkb:Streptomyces
gptkbp:bfsLayer 7