mitochondrial superoxide dismutase
GPTKB entity
Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alsoKnownAs |
gptkb:SOD2
|
| gptkbp:cofactor |
manganese
|
| gptkbp:deficiencyCauses |
oxidative stress
|
| gptkbp:discoveredBy |
gptkb:Irwin_Fridovich
|
| gptkbp:discoveredIn |
1969
|
| gptkbp:EC_number |
1.15.1.1
|
| gptkbp:encodedBy |
gptkb:SOD2_gene
|
| gptkbp:foundIn |
mitochondrial matrix
|
| gptkbp:function |
catalyzes dismutation of superoxide radicals
|
| gptkbp:gene |
gptkb:SOD2
|
| https://www.w3.org/2000/01/rdf-schema#label |
mitochondrial superoxide dismutase
|
| gptkbp:location |
mitochondria
|
| gptkbp:organism |
eukaryotes
|
| gptkbp:product |
hydrogen peroxide
oxygen |
| gptkbp:relatedTo |
gptkb:cancer
amyotrophic lateral sclerosis cardiomyopathy |
| gptkbp:role |
antioxidant defense
|
| gptkbp:structure |
homotetramer
|
| gptkbp:substrate |
gptkb:superoxide_anion
|
| gptkbp:bfsParent |
gptkb:hsa:6647
|
| gptkbp:bfsLayer |
6
|