melanocortin 4 receptor (MC4R)
GPTKB entity
Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:G_protein-coupled_receptor |
| gptkbp:alternativeName |
gptkb:MC4R
melanocortin receptor 4 |
| gptkbp:associatedWith |
obesity
|
| gptkbp:discoveredIn |
1993
|
| gptkbp:encodedBy |
MC4R gene
|
| gptkbp:enemyOf |
agouti-related peptide (AgRP)
alpha-melanocyte-stimulating hormone (α-MSH) |
| gptkbp:Entrez_Gene_ID |
4160
|
| gptkbp:expressedIn |
brain
hypothalamus |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
regulation of appetite
regulation of body weight regulation of energy homeostasis |
| https://www.w3.org/2000/01/rdf-schema#label |
melanocortin 4 receptor (MC4R)
|
| gptkbp:ligand |
agouti-related peptide (AgRP)
alpha-melanocyte-stimulating hormone (α-MSH) |
| gptkbp:locatedOnChromosome |
chromosome 18q21.3
|
| gptkbp:mutationAssociatedWith |
monogenic obesity
|
| gptkbp:OMIM |
155541
|
| gptkbp:orthologIn |
mouse Mc4r
|
| gptkbp:structureType |
seven-transmembrane domain protein
|
| gptkbp:type |
gptkb:cAMP_pathway
|
| gptkbp:UniProtID |
P32245
|
| gptkbp:bfsParent |
gptkb:agouti_signaling_peptide
|
| gptkbp:bfsLayer |
7
|