major histocompatibility complex (MHC) region
GPTKB entity
Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genomic region
|
| gptkbp:alsoKnownAs |
H-2 region (mouse)
HLA region (human) |
| gptkbp:associatedWith |
autoimmune diseases
organ transplant compatibility |
| gptkbp:containsGene |
gptkb:HLA-A
gptkb:HLA-B gptkb:HLA-C gptkb:HLA-DP gptkb:HLA-DQ gptkb:HLA-DR |
| gptkbp:discoveredIn |
1970s
|
| gptkbp:encodes |
MHC class I proteins
MHC class II proteins MHC class III proteins |
| gptkbp:function |
immune system regulation
antigen presentation |
| gptkbp:hasPolymorphism |
true
|
| https://www.w3.org/2000/01/rdf-schema#label |
major histocompatibility complex (MHC) region
|
| gptkbp:length |
~3.6 megabases (human)
|
| gptkbp:locatedOn |
gptkb:chromosome_6_(human)
|
| gptkbp:referenceGenomeCoordinates_(human,_GRCh38) |
chr6:28,477,797-33,448,354
|
| gptkbp:species |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:bfsParent |
gptkb:chromosome_6p21.3_(GABBR1)
|
| gptkbp:bfsLayer |
7
|