low-density lipoprotein receptor superfamily
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:discoveredBy |
gptkb:Michael_S._Brown
gptkb:Joseph_L._Goldstein |
| gptkbp:domain |
EGF-like domain
ligand-binding domain beta-propeller domain |
| gptkbp:encodedBy |
various genes
|
| gptkbp:foundIn |
animals
|
| gptkbp:function |
cholesterol homeostasis
endocytosis of lipoproteins |
| gptkbp:hasMember |
gptkb:LRP1
gptkb:VLDL_receptor gptkb:LRP5 gptkb:LRP6 gptkb:LDL_receptor gptkb:LRP2 gptkb:LRP8 |
| gptkbp:hasRole |
signal transduction
lipid metabolism |
| https://www.w3.org/2000/01/rdf-schema#label |
low-density lipoprotein receptor superfamily
|
| gptkbp:relatedTo |
gptkb:familial_hypercholesterolemia
|
| gptkbp:bfsParent |
gptkb:low-density_lipoprotein_receptor-related_protein_family
|
| gptkbp:bfsLayer |
8
|