|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:activeSiteResidue
|
serine hydrolase
|
|
gptkbp:associatedWith
|
pancreatitis
hypertriglyceridemia
|
|
gptkbp:cofactor
|
gptkb:apolipoprotein_C-II
|
|
gptkbp:deficiencyCauses
|
gptkb:familial_chylomicronemia_syndrome
|
|
gptkbp:discoveredBy
|
1943
|
|
gptkbp:EC_number
|
3.1.1.34
|
|
gptkbp:expressedIn
|
humans
mammals
|
|
gptkbp:foundIn
|
gptkb:adipose_tissue
gptkb:skeletal_muscle
heart
capillary endothelium
|
|
gptkbp:function
|
hydrolyzes triglycerides in lipoproteins
|
|
gptkbp:gene
|
gptkb:LPL
|
|
gptkbp:inhibitedBy
|
angiopoietin-like protein 4
apolipoprotein C-III
|
|
gptkbp:locatedOnChromosome
|
8p21.3
|
|
gptkbp:molecularWeight
|
~55 kDa
|
|
gptkbp:OMIM
|
238600
|
|
gptkbp:product
|
glycerol
free fatty acids
|
|
gptkbp:regulates
|
gptkb:insulin
gptkb:heparin
gptkb:glucocorticoids
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:substrate
|
gptkb:chylomicrons
gptkb:very_low-density_lipoproteins
|
|
gptkbp:UniProtID
|
P06858
|
|
gptkbp:bfsParent
|
gptkb:chylomicrons
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
lipoprotein lipase
|