Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:activeSiteResidue |
serine hydrolase
|
| gptkbp:associatedWith |
pancreatitis
hypertriglyceridemia |
| gptkbp:cofactor |
gptkb:apolipoprotein_C-II
|
| gptkbp:deficiencyCauses |
gptkb:familial_chylomicronemia_syndrome
|
| gptkbp:discoveredBy |
1943
|
| gptkbp:EC_number |
3.1.1.34
|
| gptkbp:expressedIn |
humans
mammals |
| gptkbp:foundIn |
gptkb:skeletal_muscle
heart adipose tissue capillary endothelium |
| gptkbp:function |
hydrolyzes triglycerides in lipoproteins
|
| gptkbp:gene |
gptkb:LPL
|
| https://www.w3.org/2000/01/rdf-schema#label |
lipoprotein lipase
|
| gptkbp:inhibitedBy |
angiopoietin-like protein 4
apolipoprotein C-III |
| gptkbp:locatedOnChromosome |
8p21.3
|
| gptkbp:molecularWeight |
~55 kDa
|
| gptkbp:OMIM |
238600
|
| gptkbp:product |
glycerol
free fatty acids |
| gptkbp:regulates |
gptkb:insulin
gptkb:heparin gptkb:glucocorticoids |
| gptkbp:structure |
homodimer
|
| gptkbp:substrate |
gptkb:chylomicrons
gptkb:very_low-density_lipoproteins |
| gptkbp:UniProtID |
P06858
|
| gptkbp:bfsParent |
gptkb:chylomicrons
|
| gptkbp:bfsLayer |
5
|