kynurenine aminotransferase (KAT)
GPTKB entity
Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:KAT
kynurenine transaminase |
| gptkbp:catalyzes |
transamination of kynurenine to kynurenic acid
|
| gptkbp:cofactor |
gptkb:pyridoxal_phosphate
|
| gptkbp:EC_number |
2.6.1.7
|
| gptkbp:foundIn |
brain
mammals liver |
| gptkbp:gene |
KYAT1
KYAT2 KYAT3 KYAT4 |
| https://www.w3.org/2000/01/rdf-schema#label |
kynurenine aminotransferase (KAT)
|
| gptkbp:inhibitedBy |
decreases kynurenic acid production
|
| gptkbp:involves |
gptkb:tryptophan_metabolism
kynurenine pathway |
| gptkbp:product |
gptkb:kynurenic_acid
|
| gptkbp:relatedTo |
epilepsy
schizophrenia neurodegenerative diseases neuroprotection |
| gptkbp:substrate |
gptkb:kynurenine
amino acid acceptor |
| gptkbp:bfsParent |
gptkb:Kynurenine_pathway
|
| gptkbp:bfsLayer |
8
|