Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
GLUR-K1
GLUR5 GLUR5A GLUR5B GLUR5C |
| gptkbp:alternativeName |
GLUR-K1
GLUR5 GLUR5A GLUR5B GLUR5C |
| gptkbp:alternativeSplicing |
produces multiple transcript variants
|
| gptkbp:associatedWith |
epilepsy
schizophrenia alcohol dependence |
| gptkbp:biologicalProcess |
synaptic transmission
nervous system development regulation of membrane potential glutamate receptor activity |
| gptkbp:cellularComponent |
gptkb:plasma_membrane
postsynaptic membrane |
| gptkbp:encodes |
Glutamate receptor ionotropic, kainate 1
|
| gptkbp:Entrez_Gene_ID |
2897
ENSG00000171189 |
| gptkbp:expressedIn |
gptkb:cerebral_cortex
brain hippocampus |
| gptkbp:function |
codes for a subunit of kainate-type glutamate receptors
|
| gptkbp:geneType |
protein-coding
|
| gptkbp:HGNC_ID |
HGNC:4583
|
| https://www.w3.org/2000/01/rdf-schema#label |
GRIK1
|
| gptkbp:interactsWith |
DLG4 (PSD-95)
GRIP1 PICK1 |
| gptkbp:length |
908
|
| gptkbp:locatedOnChromosome |
chromosome 21
21q21.3 |
| gptkbp:mutationAssociatedWith |
can alter synaptic transmission
|
| gptkbp:OMIM |
138245
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Grik1
|
| gptkbp:protein_function |
involved in synaptic plasticity
mediates excitatory neurotransmission involved in learning and memory |
| gptkbp:protein_structure |
tetrameric
|
| gptkbp:proteinFamily |
ionotropic glutamate receptor family
|
| gptkbp:significance |
potential target for antiepileptic drugs
|
| gptkbp:UniProtID |
Q13002
|
| gptkbp:bfsParent |
gptkb:kainate_receptor
gptkb:Kainate_receptor |
| gptkbp:bfsLayer |
7
|