Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
produces isoforms
|
| gptkbp:binds |
Fc region of antibodies
|
| gptkbp:discoveredBy |
gptkb:Niels_Jerne
|
| gptkbp:encodedBy |
gptkb:FCGR_genes
|
| gptkbp:expressedIn |
gptkb:natural_killer_cells
dendritic cells macrophages immune cells neutrophils |
| gptkbp:firstDescribed |
1960s
|
| gptkbp:foundIn |
vertebrates
|
| gptkbp:hasType |
gptkb:FcαR
gptkb:FcγR gptkb:FcεR |
| https://www.w3.org/2000/01/rdf-schema#label |
Fc receptors
|
| gptkbp:involvedIn |
autoimmune diseases
immune response allergic reactions immune complex clearance |
| gptkbp:medium |
inflammation
phagocytosis antibody-dependent cellular cytotoxicity |
| gptkbp:modulatedBy |
glycosylation
|
| gptkbp:proteinFamily |
gptkb:immunoglobulin_superfamily
|
| gptkbp:regulates |
antibody function
|
| gptkbp:species |
varies among species
|
| gptkbp:structure |
extracellular domain
transmembrane domain cytoplasmic tail |
| gptkbp:target |
therapeutic antibodies
|
| gptkbp:bfsParent |
gptkb:Macrophage
|
| gptkbp:bfsLayer |
5
|