|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
produces isoforms
|
|
gptkbp:binds
|
Fc region of antibodies
|
|
gptkbp:discoveredBy
|
gptkb:Niels_Jerne
|
|
gptkbp:encodedBy
|
gptkb:FCGR_genes
|
|
gptkbp:expressedIn
|
gptkb:natural_killer_cells
dendritic cells
macrophages
immune cells
neutrophils
|
|
gptkbp:firstDescribed
|
1960s
|
|
gptkbp:foundIn
|
vertebrates
|
|
gptkbp:hasType
|
gptkb:FcαR
gptkb:FcγR
gptkb:FcεR
|
|
gptkbp:involvedIn
|
gptkb:immune_response
autoimmune diseases
allergic reactions
immune complex clearance
|
|
gptkbp:medium
|
inflammation
phagocytosis
antibody-dependent cellular cytotoxicity
|
|
gptkbp:modulatedBy
|
glycosylation
|
|
gptkbp:proteinFamily
|
gptkb:immunoglobulin_superfamily
|
|
gptkbp:regulates
|
antibody function
|
|
gptkbp:species
|
varies among species
|
|
gptkbp:structure
|
extracellular domain
transmembrane domain
cytoplasmic tail
|
|
gptkbp:target
|
therapeutic antibodies
|
|
gptkbp:bfsParent
|
gptkb:immunoglobulin_superfamily
gptkb:follicular_dendritic_cells
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Fc receptors
|