Statements (60)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:drug
|
gptkbp:bfsLayer |
5
|
gptkbp:bfsParent |
gptkb:etoposide
gptkb:cyclophosphamide |
gptkbp:appointed_by |
intravenous infusion
mesna |
gptkbp:approves |
gptkb:FDA
|
gptkbp:brand |
Ifex
|
gptkbp:can_be_used_with |
gptkb:cisplatin
gptkb:etoposide gptkb:doxorubicin |
gptkbp:caused_by |
fertility issues
cardiotoxicity secondary malignancies hemorrhagic cystitis |
gptkbp:contraindication |
active infections
severe renal impairment |
gptkbp:developed_by |
gptkb:Bristol-Myers_Squibb
|
gptkbp:discovered_by |
1960s
|
https://www.w3.org/2000/01/rdf-schema#label |
ifosfamide
|
gptkbp:ingredients |
C7 H8 Cl2 N2 O2
|
gptkbp:interacts_with |
anticoagulants
other chemotherapy agents |
gptkbp:is_available_on |
oral capsule
injection solution |
gptkbp:is_monitored_by |
kidney function
blood counts |
gptkbp:is_used_for |
treating cancer
|
gptkbp:metabolism |
gptkb:acrolein
chloroacetaldehyde |
gptkbp:side_effect |
nausea
vomiting neurotoxicity bone marrow suppression |
gptkbp:suitable_for |
pregnant women
breastfeeding women |
gptkbp:type_of |
3778-73-2
|
gptkbp:used_in |
bladder cancer treatment
neuroblastoma treatment breast cancer treatment lung cancer treatment testicular cancer treatment thyroid cancer treatment lymphoma treatment ovarian cancer treatment sarcoma treatment pancreatic cancer treatment Wilms tumor treatment anal cancer treatment cervical cancer treatment choriocarcinoma treatment esophageal cancer treatment gastric cancer treatment germ cell tumors treatment head and neck cancer treatment malignant teratoma treatment neuroendocrine tumors treatment retinoblastoma treatment soft tissue sarcoma treatment vulvar cancer treatment |