Statements (74)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:DNA
|
| gptkbp:associated_with |
various genetic disorders
|
| gptkbp:contains |
the gene for the protein dystrophin-associated glycoprotein complex
the gene for the enzyme phenylalanine hydroxylase the gene for the protein apolipoprotein E the gene for the protein collagen type IV the gene for the protein dystrophin the gene for the protein glutamate receptor the gene for the protein insulin receptor the gene for the protein interleukin-6 the gene for the protein myelin basic protein the gene for the protein myeloperoxidase the gene for the protein neurofibromin the gene for the protein tumor necrosis factor-alpha |
| gptkbp:has |
multiple single nucleotide polymorphisms (SNPs)
|
| https://www.w3.org/2000/01/rdf-schema#label |
human chromosome 16
|
| gptkbp:inherits_from |
both parents
|
| gptkbp:involved_in |
the regulation of metabolism
|
| gptkbp:is_analyzed_in |
genome-wide association studies (GWAS)
|
| gptkbp:is_associated_with |
gptkb:neurodegenerative_diseases
mental health disorders cardiovascular diseases chronic inflammation developmental disorders cognitive disorders |
| gptkbp:is_characterized_by |
gene duplications
high gene density high recombination rates repetitive sequences structural variations |
| gptkbp:is_involved_in |
cell signaling pathways
cellular differentiation neurodevelopmental processes the immune response the regulation of gene expression chromosomal rearrangements the development of the nervous system the development of various tissues the immune system regulation the regulation of cell growth the response to environmental stress |
| gptkbp:is_linked_to |
metabolic disorders
autoimmune diseases chronic diseases obesity schizophrenia aging processes fertility issues endocrine disorders autism spectrum disorders metabolic syndromes various hereditary conditions |
| gptkbp:is_part_of |
the study of human evolution
the human genome the 23 pairs of chromosomes in humans the genetic basis of human traits the human genetic architecture |
| gptkbp:is_studied_for |
cancer research
its evolutionary significance its implications in genetic testing its implications in personalized medicine its role in gene therapy its role in genetic counseling its role in hereditary diseases its role in population genetics |
| gptkbp:is_studied_in |
genetic research
|
| gptkbp:length |
90 million base pairs
|
| gptkbp:location |
located on the 16th chromosome of the human genome
|
| gptkbp:number_of_genes |
approximately 1,000
|
| gptkbp:bfsParent |
gptkb:AXIN1
gptkb:FUS_gene gptkb:CYBA gptkb:FANCF |
| gptkbp:bfsLayer |
6
|