|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
gptkb:prealbumin
TBPA (thyroxine-binding prealbumin)
|
|
gptkbp:binds
|
thyroxine (T4)
retinol-binding protein
|
|
gptkbp:discoveredBy
|
Richard D. Sletten
|
|
gptkbp:discoveredIn
|
1958
|
|
gptkbp:expressedIn
|
liver
choroid plexus
|
|
gptkbp:fullName
|
gptkb:transthyretin
|
|
gptkbp:function
|
transports thyroxine
transports retinol (vitamin A)
|
|
gptkbp:gene
|
gptkb:TTR
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
human TTR
|
|
gptkbp:length
|
127 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_18
|
|
gptkbp:location
|
gptkb:plasma
cerebrospinal fluid
|
|
gptkbp:medicalUse
|
biomarker for nutritional status
|
|
gptkbp:molecularWeight
|
approximately 14 kDa (monomer)
|
|
gptkbp:mutationAssociatedWith
|
gptkb:familial_amyloid_cardiomyopathy
gptkb:familial_amyloid_polyneuropathy
gptkb:senile_systemic_amyloidosis
|
|
gptkbp:OMIM
|
176300
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
gptkb:1F41
|
|
gptkbp:structure
|
homotetramer
|
|
gptkbp:UniProtID
|
gptkb:P02766
|
|
gptkbp:bfsParent
|
gptkb:Ttr
|
|
gptkbp:bfsLayer
|
8
|