human SDHB

GPTKB entity

Statements (29)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:SDH2
Iron-sulfur subunit of succinate dehydrogenase
SDH iron-sulfur protein
gptkbp:associatedWith SDHB-related hereditary paraganglioma-pheochromocytoma syndrome
gptkbp:component succinate dehydrogenase complex (Complex II)
gptkbp:contains iron-sulfur clusters
gptkbp:encodedBy gptkb:SDHB_gene
gptkbp:Entrez_Gene_ID 6390
gptkbp:enzymeCommissionNumber EC 1.3.5.1
gptkbp:fullName Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
gptkbp:function catalyzes oxidation of succinate to fumarate in the mitochondrial electron transport chain
gptkbp:gene gptkb:SDHB
gptkbp:HGNC_ID gptkb:HGNC:10680
https://www.w3.org/2000/01/rdf-schema#label human SDHB
gptkbp:locatedOnChromosome gptkb:1p36.13
gptkbp:location mitochondrial inner membrane
gptkbp:molecularWeight 30 kDa
gptkbp:mutationAssociatedWith gptkb:pheochromocytoma
renal cell carcinoma
hereditary paraganglioma
gptkbp:OMIM 185470
gptkbp:organism gptkb:Homo_sapiens
gptkbp:PDB 1ZOY
gptkbp:RefSeq NP_003000.2
gptkbp:subunit gptkb:mitochondrial_respiratory_chain_complex_II
gptkbp:UniProtID gptkb:P21912
gptkbp:bfsParent gptkb:SDH2
gptkbp:bfsLayer 8