gptkbp:instanceOf
|
gptkb:protein
|
gptkbp:alternativeName
|
gptkb:SDH2
Iron-sulfur subunit of succinate dehydrogenase
SDH iron-sulfur protein
|
gptkbp:associatedWith
|
SDHB-related hereditary paraganglioma-pheochromocytoma syndrome
|
gptkbp:component
|
succinate dehydrogenase complex (Complex II)
|
gptkbp:contains
|
iron-sulfur clusters
|
gptkbp:encodedBy
|
gptkb:SDHB_gene
|
gptkbp:Entrez_Gene_ID
|
6390
|
gptkbp:enzymeCommissionNumber
|
EC 1.3.5.1
|
gptkbp:fullName
|
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
|
gptkbp:function
|
catalyzes oxidation of succinate to fumarate in the mitochondrial electron transport chain
|
gptkbp:gene
|
gptkb:SDHB
|
gptkbp:HGNC_ID
|
gptkb:HGNC:10680
|
https://www.w3.org/2000/01/rdf-schema#label
|
human SDHB
|
gptkbp:locatedOnChromosome
|
gptkb:1p36.13
|
gptkbp:location
|
mitochondrial inner membrane
|
gptkbp:molecularWeight
|
30 kDa
|
gptkbp:mutationAssociatedWith
|
gptkb:pheochromocytoma
renal cell carcinoma
hereditary paraganglioma
|
gptkbp:OMIM
|
185470
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
gptkbp:PDB
|
1ZOY
|
gptkbp:RefSeq
|
NP_003000.2
|
gptkbp:subunit
|
gptkb:mitochondrial_respiratory_chain_complex_II
|
gptkbp:UniProtID
|
gptkb:P21912
|
gptkbp:bfsParent
|
gptkb:SDH2
|
gptkbp:bfsLayer
|
8
|