heterotrimeric G-proteins

URI: https://gptkb.org/entity/heterotrimeric_G-proteins

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:activatedBy	gptkb:G_protein-coupled_receptors
gptkbp:alternativeName	G-protein heterotrimer GTP-binding protein complex
gptkbp:binds	gptkb:guanosine_diphosphate_(GDP) gptkb:guanosine_triphosphate_(GTP)
gptkbp:composedOf	gptkb:Gα_subunit gptkb:Gβ_subunit gptkb:Gγ_subunit
gptkbp:decommissioned	hydrolysis of GTP
gptkbp:discoveredBy	gptkb:Martin_Rodbell gptkb:Alfred_G._Gilman
gptkbp:foundIn	eukaryotic cells
gptkbp:function	signal transduction
https://www.w3.org/2000/01/rdf-schema#label	heterotrimeric G-proteins
gptkbp:locale	gptkb:plasma_membrane
gptkbp:molecularWeight	~80 kDa
gptkbp:NobelPrizeYear	1994 Physiology or Medicine
gptkbp:proteinFamily	GNA family GNB family GNG family
gptkbp:regulates	gptkb:phospholipase_C ion channels adenylyl cyclase
gptkbp:relatedTo	monomeric G-proteins
gptkbp:role	sensory perception hormone signaling neurotransmitter signaling
gptkbp:subunit	gptkb:Gα12/13 gptkb:Gαq Gαi Gαs
gptkbp:bfsParent	gptkb:G-proteins
gptkbp:bfsLayer	8