chronic graft-versus-host disease
GPTKB entity
Statements (41)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
immune system disorder |
| gptkbp:affects |
gptkb:skin
lungs gastrointestinal tract liver eyes mouth |
| gptkbp:cause |
malnutrition
chronic pain infections organ dysfunction fibrosis |
| gptkbp:causedBy |
allogeneic hematopoietic stem cell transplantation
|
| gptkbp:complication |
hematopoietic stem cell transplantation
|
| gptkbp:field |
immunology
hematology |
| gptkbp:firstDescribed |
1970s
|
| gptkbp:hasAcuteForm |
gptkb:acute_graft-versus-host_disease
|
| gptkbp:hasEpidemiology |
affects 30-70% of allogeneic transplant recipients
|
| https://www.w3.org/2000/01/rdf-schema#label |
chronic graft-versus-host disease
|
| gptkbp:ICD-10_code |
T86.0
|
| gptkbp:MeSH_ID |
gptkb:D005778
|
| gptkbp:mortalityRate |
10-30%
|
| gptkbp:riskFactor |
female donor to male recipient
older donor age allogeneic bone marrow transplant |
| gptkbp:symptom |
diarrhea
jaundice shortness of breath rash joint stiffness dry mouth dry eyes |
| gptkbp:treatment |
gptkb:rituximab
gptkb:ibrutinib corticosteroids immunosuppressive drugs extracorporeal photopheresis |
| gptkbp:bfsParent |
gptkb:graft-versus-host_disease
|
| gptkbp:bfsLayer |
6
|