glutamate oxaloacetate transaminase

URI: https://gptkb.org/entity/glutamate_oxaloacetate_transaminase
GPTKB entity
Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:abbreviation gptkb:GOT
AST
gptkbp:alsoKnownAs gptkb:aspartate_aminotransferase
gptkbp:catalyzes transamination between aspartate and alpha-ketoglutarate
gptkbp:cofactor gptkb:pyridoxal_phosphate
gptkbp:EC_number 2.6.1.1
gptkbp:foundIn gptkb:cytoplasm
mitochondria
gptkbp:gene_symbol_(cytoplasmic) gptkb:GOT1
gptkbp:gene_symbol_(mitochondrial) gptkb:GOT2
https://www.w3.org/2000/01/rdf-schema#label glutamate oxaloacetate transaminase
gptkbp:involves gptkb:urea_cycle
amino acid metabolism
gluconeogenesis
gptkbp:measures blood tests
gptkbp:presentIn animals
plants
microorganisms
gptkbp:product gptkb:oxaloacetate
glutamate
gptkbp:significance elevated in liver disease
elevated in myocardial infarction
gptkbp:structure homodimer
gptkbp:substrate gptkb:alpha-ketoglutarate
gptkb:aspartate
gptkbp:UniProt_ID_(GOT1) P17174
gptkbp:UniProt_ID_(GOT2) P00505
gptkbp:usedFor biomarker for liver function
gptkbp:bfsParent gptkb:aspartate_aminotransferase
gptkbp:bfsLayer 7