glutamate decarboxylase enzyme (GAD67)
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alsoKnownAs |
gptkb:GAD67
|
| gptkbp:catalyzes |
conversion of glutamate to GABA
|
| gptkbp:cofactor |
gptkb:pyridoxal_phosphate
|
| gptkbp:EC_number |
4.1.1.15
|
| gptkbp:encodedBy |
gptkb:GAD1_gene
|
| gptkbp:Entrez_Gene_ID |
gptkb:GAD1
|
| gptkbp:expressedIn |
neurons
|
| gptkbp:foundIn |
central nervous system
|
| gptkbp:function |
GABA synthesis
|
| https://www.w3.org/2000/01/rdf-schema#label |
glutamate decarboxylase enzyme (GAD67)
|
| gptkbp:inhibitedBy |
gptkb:3-mercaptopropionic_acid
|
| gptkbp:involves |
epilepsy
schizophrenia type 1 diabetes (as autoantigen) |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_2q31
|
| gptkbp:molecularWeight |
67 kDa
|
| gptkbp:relatedTo |
gptkb:GAD65
|
| gptkbp:species |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:subcellularLocation |
cytosol
|
| gptkbp:bfsParent |
gptkb:GAD1
|
| gptkbp:bfsLayer |
7
|