glutamate--ammonia ligase

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:CASNumber 9013-53-0
gptkbp:catalyzes ATP + L-glutamate + NH3 → ADP + phosphate + L-glutamine
gptkbp:cofactor gptkb:ATP
gptkbp:EC_number 6.3.1.2
gptkbp:foundIn gptkb:Bacteria
animals
plants
gptkbp:function synthesizes glutamine from glutamate and ammonia
gptkbp:gene gptkb:GLUL
https://www.w3.org/2000/01/rdf-schema#label glutamate--ammonia ligase
gptkbp:inhibitedBy gptkb:AMP
gptkb:CTP
gptkb:glutamine
tryptophan
adenosine monophosphate
serine
glycine
alanine
histidine
carbamoyl phosphate
glucosamine-6-phosphate
gptkbp:involves nitrogen metabolism
gptkbp:location gptkb:cytoplasm
gptkbp:otherName gptkb:glutamine_synthetase
gptkbp:regulates allosteric regulation
covalent modification
gptkbp:significance congenital glutamine deficiency
hyperammonemia (if deficient)
gptkbp:structure multimeric protein
gptkbp:UniProtID P15104
gptkbp:bfsParent gptkb:Glutamine_synthetase
gptkbp:bfsLayer 7