glucose-6-phosphate 1-dehydrogenase
GPTKB entity
Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:biologicalProcess |
oxidoreductase activity
|
| gptkbp:catalyzes |
oxidation of glucose-6-phosphate to 6-phosphoglucono-δ-lactone
|
| gptkbp:cofactor |
NADP+
|
| gptkbp:deficiencyCauses |
glucose-6-phosphate dehydrogenase deficiency
|
| gptkbp:EC_number |
1.1.1.49
|
| gptkbp:foundIn |
gptkb:Bacteria
animals humans plants |
| gptkbp:gene |
gptkb:G6PD
|
| https://www.w3.org/2000/01/rdf-schema#label |
glucose-6-phosphate 1-dehydrogenase
|
| gptkbp:importantFor |
protects cells from oxidative damage
|
| gptkbp:location |
gptkb:cytoplasm
|
| gptkbp:pathway |
gptkb:pentose_phosphate_pathway
|
| gptkbp:product |
gptkb:6-phosphoglucono-δ-lactone
NADPH |
| gptkbp:regulates |
activated by NADP+
inhibited by NADPH |
| gptkbp:substrate |
gptkb:glucose-6-phosphate
NADP+ |
| gptkbp:UniProtID |
P11413 (human)
|
| gptkbp:bfsParent |
gptkb:G6PD_gene
|
| gptkbp:bfsLayer |
7
|