|
gptkbp:instanceOf
|
gptkb:drug
sulfonylurea
|
|
gptkbp:ATCCode
|
A10BB01
|
|
gptkbp:brand
|
Diabeta
Glynase
Micronase
Semi-Daonil
|
|
gptkbp:CASNumber
|
10238-21-8
|
|
gptkbp:color
|
white
|
|
gptkbp:contraindication
|
type 1 diabetes
pregnancy
|
|
gptkbp:discoveredBy
|
gptkb:Boehringer_Mannheim
|
|
gptkbp:drugClass
|
antidiabetic
hypoglycemic agent
|
|
gptkbp:eliminationHalfLife
|
10 hours
|
|
gptkbp:excretion
|
urine
bile
|
|
gptkbp:hasMolecularFormula
|
C23H28ClN3O5S
|
|
gptkbp:hasTabletForm
|
yes
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
glibenclamide
|
|
gptkbp:interactsWith
|
gptkb:rifampicin
gptkb:beer
gptkb:warfarin
gptkb:thiazide_diuretics
beta blockers
|
|
gptkbp:introducedIn
|
1969
|
|
gptkbp:KEGGID
|
D00588
|
|
gptkbp:lactation
|
not recommended
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
stimulates insulin release
|
|
gptkbp:MedlinePlusID
|
a684036
|
|
gptkbp:MeSH_ID
|
D005931
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
494.004 g/mol
|
|
gptkbp:overdoseSymptoms
|
severe hypoglycemia
|
|
gptkbp:pregnancyCategory
|
C (US)
B (Australia)
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1431
3367
3488
|
|
gptkbp:riskFactor
|
hypoglycemia in elderly
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
gptkb:hypoglycemia
weight gain
|
|
gptkbp:solubility
|
practically insoluble in water
|
|
gptkbp:synonym
|
gptkb:glyburide
|
|
gptkbp:UNII
|
SX6K58TVWC
|
|
gptkbp:usedFor
|
gptkb:type_2_diabetes
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
included
|
|
gptkbp:bfsParent
|
gptkb:glyburide
|
|
gptkbp:bfsLayer
|
6
|