gamma-aminobutyric acid receptor subunit beta-2

URI: https://gptkb.org/entity/gamma-aminobutyric_acid_receptor_subunit_beta-2
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeSplicing yes
gptkbp:associatedWith bipolar disorder
epilepsy
schizophrenia
gptkbp:binds gptkb:gamma-aminobutyric_acid_(GABA)
gptkbp:component gptkb:GABA-A_receptor
gptkbp:encodedBy gptkb:GABRB2_gene
gptkbp:Entrez_Gene_ID 2561
gptkbp:formsComplexWith alpha subunits of GABA-A receptor
gamma subunits of GABA-A receptor
gptkbp:foundIn gptkb:human
mammals
gptkbp:function mediates inhibitory neurotransmission
https://www.w3.org/2000/01/rdf-schema#label gamma-aminobutyric acid receptor subunit beta-2
gptkbp:locatedOnChromosome 5q34
gptkbp:location gptkb:cell_membrane
postsynaptic membrane
gptkbp:modulatedBy gptkb:benzodiazepines
ethanol
barbiturates
neurosteroids
anesthetics
gptkbp:molecularWeight 54 kDa
gptkbp:structure transmembrane protein
gptkbp:synonym GABA(A) receptor subunit beta-2
GABRB2
gamma-aminobutyric acid type A receptor beta2 subunit
gptkbp:transmembraneDomains 4
gptkbp:UniProtID P47870
gptkbp:bfsParent gptkb:GABRB2_gene
gptkbp:bfsLayer 7