gamma-aminobutyrate aminotransferase
GPTKB entity
Statements (18)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:enzyme
|
gptkbp:alternativeName |
gptkb:GABA-T
gptkb:GABA_transaminase |
gptkbp:associatedWith |
epilepsy (when deficient)
|
gptkbp:biologicalProcess |
aminotransferase activity
neurotransmitter catabolic process |
gptkbp:catalyzes |
conversion of 4-aminobutanoate and 2-oxoglutarate to succinate semialdehyde and L-glutamate
|
gptkbp:cofactor |
gptkb:pyridoxal_phosphate
|
gptkbp:EC_number |
gptkb:2.6.1.19
|
gptkbp:foundIn |
mitochondria
|
gptkbp:gene |
gptkb:ABAT
|
https://www.w3.org/2000/01/rdf-schema#label |
gamma-aminobutyrate aminotransferase
|
gptkbp:inhibitedBy |
gptkb:vigabatrin
|
gptkbp:involves |
gptkb:GABA_shunt
|
gptkbp:locatedIn |
human chromosome 16p13.2
|
gptkbp:UniProtID |
P80404
|
gptkbp:bfsParent |
gptkb:ABAT_gene
|
gptkbp:bfsLayer |
7
|