gamma-aminobutyrate aminotransferase

GPTKB entity

Statements (18)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName gptkb:GABA-T
gptkb:GABA_transaminase
gptkbp:associatedWith epilepsy (when deficient)
gptkbp:biologicalProcess aminotransferase activity
neurotransmitter catabolic process
gptkbp:catalyzes conversion of 4-aminobutanoate and 2-oxoglutarate to succinate semialdehyde and L-glutamate
gptkbp:cofactor gptkb:pyridoxal_phosphate
gptkbp:EC_number gptkb:2.6.1.19
gptkbp:foundIn mitochondria
gptkbp:gene gptkb:ABAT
https://www.w3.org/2000/01/rdf-schema#label gamma-aminobutyrate aminotransferase
gptkbp:inhibitedBy gptkb:vigabatrin
gptkbp:involves gptkb:GABA_shunt
gptkbp:locatedIn human chromosome 16p13.2
gptkbp:UniProtID P80404
gptkbp:bfsParent gptkb:ABAT_gene
gptkbp:bfsLayer 7