Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:4-aminobutyrate_aminotransferase
|
| gptkbp:associatedWith |
gptkb:GABAergic_signaling
epilepsy |
| gptkbp:cofactor |
gptkb:pyridoxal_phosphate
|
| gptkbp:EC_number |
gptkb:2.6.1.19
|
| gptkbp:foundIn |
animals
humans plants |
| gptkbp:fullName |
gamma-aminobutyric acid transaminase
|
| gptkbp:function |
catalyzes the conversion of GABA to succinic semialdehyde
|
| gptkbp:gene |
gptkb:ABAT
|
| https://www.w3.org/2000/01/rdf-schema#label |
GABA-T
|
| gptkbp:inhibitedBy |
gptkb:vigabatrin
|
| gptkbp:locatedOnChromosome |
16p13.2
|
| gptkbp:location |
mitochondria
|
| gptkbp:mutationAssociatedWith |
gptkb:GABA-transaminase_deficiency
|
| gptkbp:role |
gptkb:GABA_shunt
neurotransmitter metabolism |
| gptkbp:structure |
homodimer
|
| gptkbp:UniProtID |
P80404
|
| gptkbp:bfsParent |
gptkb:4-aminobutyrate_aminotransferase
gptkb:ABAT_gene |
| gptkbp:bfsLayer |
7
|