Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
RNA molecule
|
| gptkbp:application |
genome editing
gene activation gene knockout gene repression |
| gptkbp:binds |
gptkb:Cas9_protein
target DNA |
| gptkbp:composedOf |
gptkb:crRNA
gptkb:tracrRNA |
| gptkbp:discoveredIn |
2012
|
| gptkbp:fullName |
gptkb:guide_RNA
|
| gptkbp:function |
guides Cas9 to target DNA sequence
|
| https://www.w3.org/2000/01/rdf-schema#label |
gRNA
|
| gptkbp:length |
~100 nucleotides
|
| gptkbp:origin |
synthetic or natural
|
| gptkbp:relatedTo |
gptkb:CRISPR
gptkb:Cas9 |
| gptkbp:sequenceSpecificity |
determined by spacer region
|
| gptkbp:spacerRegionLength |
~20 nucleotides
|
| gptkbp:usedBy |
researchers in molecular biology
|
| gptkbp:usedIn |
gptkb:CRISPR-Cas9_system
|
| gptkbp:bfsParent |
gptkb:guide_RNA
|
| gptkbp:bfsLayer |
6
|