Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
complement factor H
|
| gptkbp:associatedWith |
gptkb:atypical_hemolytic_uremic_syndrome
gptkb:C3_glomerulopathy age-related macular degeneration |
| gptkbp:encodedBy |
CFH gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
inhibits alternative pathway of complement activation
regulation of the complement system |
| https://www.w3.org/2000/01/rdf-schema#label |
factor H
|
| gptkbp:interactsWith |
gptkb:C3b
factor I |
| gptkbp:locatedOnChromosome |
1q32
|
| gptkbp:location |
gptkb:plasma
|
| gptkbp:molecularWeight |
~155 kDa
|
| gptkbp:prevention |
complement-mediated damage to host tissue
|
| gptkbp:regulates |
complement activation on host cells
|
| gptkbp:species |
gptkb:human
gptkb:mouse right |
| gptkbp:structure |
composed of 20 short consensus repeats (SCRs)
|
| gptkbp:bfsParent |
gptkb:iC3b
|
| gptkbp:bfsLayer |
7
|