Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
glomerular disease |
| gptkbp:affects |
gptkb:kidney
|
| gptkbp:associatedWith |
alternative complement pathway dysregulation
|
| gptkbp:cause |
hematuria
proteinuria renal insufficiency |
| gptkbp:characterizedBy |
dominant C3 complement deposition in glomeruli
|
| gptkbp:diagnosedBy |
immunofluorescence microscopy
kidney biopsy |
| gptkbp:firstDescribed |
2007
|
| https://www.w3.org/2000/01/rdf-schema#label |
C3 glomerulopathy
|
| gptkbp:ICD-10_code |
N03.8
|
| gptkbp:includes |
C3 glomerulonephritis
dense deposit disease |
| gptkbp:riskFactor |
genetic mutations in complement regulatory proteins
autoantibodies to complement proteins |
| gptkbp:synonym |
gptkb:C3G
|
| gptkbp:treatment |
immunosuppressive therapy
complement inhibitors |
| gptkbp:bfsParent |
gptkb:CFHR1
gptkb:factor_H gptkb:Kidney_Biopsy |
| gptkbp:bfsLayer |
8
|