atypical hemolytic uremic syndrome

URI: https://gptkb.org/entity/atypical_hemolytic_uremic_syndrome
GPTKB entity
Statements (43)
Predicate Object
gptkbp:instanceOf gptkb:disease
gptkbp:abbreviation gptkb:aHUS
gptkbp:cause genetic disorder
autoantibodies
complement system dysregulation
gptkbp:complication chronic kidney disease
end-stage renal disease
gptkbp:differentialDiagnosis gptkb:typical_hemolytic_uremic_syndrome
thrombotic thrombocytopenic purpura
gptkbp:firstDescribed 1955
gptkbp:frequency rare
gptkbp:gene gptkb:CFI
gptkb:CD46
gptkb:CFH
gptkb:DGKE
gptkb:THBD
gptkb:CFB
C3
https://www.w3.org/2000/01/rdf-schema#label atypical hemolytic uremic syndrome
gptkbp:ICD-10_code D59.3
gptkbp:inheritance autosomal dominant
autosomal recessive
gptkbp:MeSH_ID D006471
gptkbp:not_caused_by gptkb:Shiga_toxin-producing_Escherichia_coli
gptkbp:OMIM 235400
gptkbp:onset any age
gptkbp:riskFactor transplantation
infection
pregnancy
gptkbp:specialty nephrology
hematology
gptkbp:symptom gptkb:anemia
thrombocytopenia
acute kidney injury
gptkbp:treatment gptkb:eculizumab
supportive care
plasma exchange
gptkbp:bfsParent gptkb:Soliris
gptkb:Ultomiris
gptkb:chromosome_1q32
gptkb:eculizumab
gptkb:ravulizumab
gptkbp:bfsLayer 7