atypical hemolytic uremic syndrome

URI: https://gptkb.org/entity/atypical_hemolytic_uremic_syndrome
GPTKB entity
Statements (39)
Predicate Object
gptkbp:instanceOf gptkb:disease
gptkbp:abbreviation gptkb:aHUS
gptkbp:cause gptkb:genetic_disorder
autoantibodies
complement system dysregulation
gptkbp:complication chronic kidney disease
end-stage renal disease
gptkbp:differentialDiagnosis gptkb:typical_hemolytic_uremic_syndrome
thrombotic thrombocytopenic purpura
gptkbp:firstDescribed 1955
gptkbp:frequency rare
gptkbp:gene gptkb:CFI
gptkb:CD46
gptkb:CFH
gptkb:DGKE
gptkb:THBD
gptkb:CFB
C3
gptkbp:ICD-10_code D59.3
gptkbp:inheritance autosomal dominant
autosomal recessive
gptkbp:MeSH_ID D006471
gptkbp:not_caused_by gptkb:Shiga_toxin-producing_Escherichia_coli
gptkbp:OMIM 235400
gptkbp:onset any age
gptkbp:riskFactor transplantation
infection
pregnancy
gptkbp:specialty nephrology
hematology
gptkbp:symptom gptkb:anemia
gptkb:acute_kidney_injury
thrombocytopenia
gptkbp:treatment gptkb:eculizumab
supportive care
plasma exchange
gptkbp:bfsParent gptkb:chromosome_1q32
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label atypical hemolytic uremic syndrome