extranodal marginal zone lymphoma

URI: https://gptkb.org/entity/extranodal_marginal_zone_lymphoma
GPTKB entity
Statements (51)
Predicate Object
gptkbp:instanceOf leukemia
gptkbp:alsoKnownAs gptkb:MALT_lymphoma
gptkbp:associatedWith gptkb:Helicobacter_pylori_infection
gptkbp:commonIn adults
gptkbp:diagnosedBy biopsy
immunohistochemistry
gptkbp:firstDescribed 1983
gptkbp:gender slightly more common in females
gptkbp:geneticAbnormality API2-MALT1 fusion
t(11;18)(q21;q21) translocation
https://www.w3.org/2000/01/rdf-schema#label extranodal marginal zone lymphoma
gptkbp:ICD-10_code C88.4
gptkbp:incidence rare
gptkbp:marking CD20 positive
CD10 negative
BCL2 positive
CD5 negative
CD79a positive
Cyclin D1 negative
gptkbp:medianAge 60
gptkbp:occurredIn gptkb:breast
gptkb:skin
gptkb:small_intestine
ocular adnexa
gptkbp:origin gptkb:B_cell
gptkbp:originatedIn gptkb:mucosa-associated_lymphoid_tissue
gptkbp:prognosis generally favorable
gptkbp:progression indolent
gptkbp:rareIn children
gptkbp:relapseRate low
gptkbp:riskFactor autoimmune disease
chronic inflammation
Hashimoto thyroiditis
Sjogren syndrome
gptkbp:stagingSystem Ann Arbor system
gptkbp:subspecies gptkb:marginal_zone_lymphoma
gptkbp:symptom abdominal pain
weight loss
dyspepsia
gptkbp:transformsInto diffuse large B-cell lymphoma
gptkbp:treatment radiation therapy
chemotherapy
immunotherapy
antibiotic therapy
gptkbp:website gptkb:thyroid
gptkb:cancer
salivary gland
stomach
gptkbp:WHOClassification mature B-cell neoplasm
gptkbp:bfsParent gptkb:marginal_zone_lymphoma
gptkbp:bfsLayer 7