MALT lymphoma

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:disease
leukemia
gptkbp:affects gptkb:breast
gptkb:thyroid
gptkb:cancer
gptkb:mucosa-associated_lymphoid_tissue
gptkb:skin
salivary gland
stomach
ocular adnexa
gptkbp:associatedWith gptkb:Helicobacter_pylori_infection
gptkb:Hashimoto's_thyroiditis
autoimmune diseases
Sjogren's syndrome
gptkbp:canBeDisseminated yes
gptkbp:canBeIndolent yes
gptkbp:canBeLocalized yes
gptkbp:cellOrigin gptkb:B_cell
gptkbp:commonIn adults
elderly
gptkbp:diagnosedBy imaging
endoscopy
biopsy
gptkbp:firstDescribed 1983
gptkbp:fullName Mucosa-associated lymphoid tissue lymphoma
gptkbp:gender slightly more common in females
gptkbp:geneticAbnormality API2-MALT1 fusion
t(11;18)(q21;q21) translocation
https://www.w3.org/2000/01/rdf-schema#label MALT lymphoma
gptkbp:ICD-10_code C88.4
gptkbp:prognosis generally favorable
gptkbp:rareIn children
gptkbp:relapsePossible yes
gptkbp:riskFactor persistent infection
chronic inflammation
gptkbp:stagingSystem Ann Arbor system
gptkbp:subspecies extranodal marginal zone B-cell lymphoma
gptkbp:symptom abdominal pain
fatigue
weight loss
dyspepsia
gptkbp:transformsInto diffuse large B-cell lymphoma
gptkbp:treatment antibiotics
radiation therapy
chemotherapy
immunotherapy
gptkbp:WHOClassification mature B-cell neoplasm
gptkbp:bfsParent gptkb:Helicobacter_pylori_infection
gptkb:Helicobacter_pylori
gptkbp:bfsLayer 6