dihydrotestosterone (DHT)

URI: https://gptkb.org/entity/dihydrotestosterone_(DHT)

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:androgen gptkb:hormone
gptkbp:associatedWith	gptkb:androgenic_alopecia gptkb:benign_prostatic_hyperplasia prostate cancer
gptkbp:binds	gptkb:androgen_receptor
gptkbp:CASNumber	521-18-6
gptkbp:category	gptkb:anabolic_steroid gptkb:hormone gptkb:biological_molecule sex hormone endogenous androgen
gptkbp:chemicalFormula	C19H30O2
gptkbp:derivedFrom	testosterone
gptkbp:foundIn	humans other mammals
gptkbp:inhibitedBy	gptkb:dutasteride gptkb:finasteride
gptkbp:IUPACName	gptkb:17β-hydroxy-5α-androstan-3-one
gptkbp:meltingPoint	178–180 °C
gptkbp:MeSH_ID	gptkb:D004110
gptkbp:metabolism	gptkb:3α-hydroxysteroid_dehydrogenase
gptkbp:molecularWeight	290.44 g/mol
gptkbp:producedBy	gptkb:prostate liver adrenal glands testes hair follicles
gptkbp:PubChem_CID	gptkb:CHEMBL1179 gptkb:DB00624 10635 CHEBI:16464
gptkbp:role	male sexual development sebaceous gland activity hair growth regulation prostate development secondary sex characteristics
gptkbp:strongerAffinityThan	testosterone
gptkbp:synthesisType	gptkb:5α-reductase
gptkbp:UNII	OKG364O896
gptkbp:bfsParent	gptkb:androgenic_alopecia gptkb:oxandrolone
gptkbp:bfsLayer	8
https://www.w3.org/2000/01/rdf-schema#label	dihydrotestosterone (DHT)