dihydrotestosterone (DHT)

URI: https://gptkb.org/entity/dihydrotestosterone_(DHT)
GPTKB entity
Statements (44)
Predicate Object
gptkbp:instanceOf hormone
androgen
gptkbp:associatedWith gptkb:androgenic_alopecia
gptkb:benign_prostatic_hyperplasia
prostate cancer
gptkbp:binds gptkb:androgen_receptor
gptkbp:CASNumber 521-18-6
gptkbp:category hormone
biological molecule
anabolic steroid
sex hormone
endogenous androgen
gptkbp:chemicalFormula C19H30O2
gptkbp:derivedFrom testosterone
gptkbp:foundIn humans
other mammals
https://www.w3.org/2000/01/rdf-schema#label dihydrotestosterone (DHT)
gptkbp:inhibitedBy gptkb:dutasteride
gptkb:finasteride
gptkbp:IUPACName gptkb:17β-hydroxy-5α-androstan-3-one
gptkbp:meltingPoint 178–180 °C
gptkbp:MeSH_ID gptkb:D004110
gptkbp:metabolism gptkb:3α-hydroxysteroid_dehydrogenase
gptkbp:molecularWeight 290.44 g/mol
gptkbp:producedBy gptkb:prostate
liver
adrenal glands
testes
hair follicles
gptkbp:PubChem_CID gptkb:CHEMBL1179
gptkb:DB00624
10635
CHEBI:16464
gptkbp:role male sexual development
sebaceous gland activity
hair growth regulation
prostate development
secondary sex characteristics
gptkbp:strongerAffinityThan testosterone
gptkbp:synthesisType gptkb:5α-reductase
gptkbp:UNII OKG364O896
gptkbp:bfsParent gptkb:androgenic_alopecia
gptkb:oxandrolone
gptkbp:bfsLayer 8