dehydroepiandrosterone (DHEA)
GPTKB entity
Statements (61)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
hormone
|
| gptkbp:ATCCode |
G03XX01
|
| gptkbp:biosynthesized_from |
gptkb:pregnenolone
|
| gptkbp:CASNumber |
53-43-0
|
| gptkbp:chemicalFormula |
C19H28O2
|
| gptkbp:contraindication |
pregnancy
breastfeeding hormone-sensitive cancers |
| gptkbp:convertedTo |
gptkb:androstenedione
gptkb:estradiol estrone testosterone |
| gptkbp:excreted_as |
DHEA sulfate (DHEAS)
|
| gptkbp:firstIsolatedFrom |
1934
|
| gptkbp:foundIn |
adrenal glands
|
| gptkbp:hasInChIKey |
FMGSKWYWMVUUJI-XGXHKTLJSA-N
|
| gptkbp:hasUNII |
AE45V16LKN
|
| gptkbp:heldBy |
neurosteroid
prohormone C19 steroid endogenous hormone androgen precursor controlled substance (Canada, Australia) over-the-counter supplement (US) unscheduled drug (US) |
| https://www.w3.org/2000/01/rdf-schema#label |
dehydroepiandrosterone (DHEA)
|
| gptkbp:IUPACName |
3β-hydroxyandrost-5-en-17-one
|
| gptkbp:KEGGID |
C00585
|
| gptkbp:levels_decline_with |
age
|
| gptkbp:levels_peak_at |
age 20–30
|
| gptkbp:meltingPoint |
148–151 °C
|
| gptkbp:metabolite_of |
cholesterol
|
| gptkbp:molecularWeight |
288.42 g/mol
|
| gptkbp:predecessor |
testosterone
estrogens |
| gptkbp:producedBy |
brain
adrenal cortex gonads |
| gptkbp:PubChem_CID |
5670
5881 CHEMBL118 DB02789 |
| gptkbp:regulates |
gptkb:pituitary_gland
gptkb:ACTH |
| gptkbp:sideEffect |
hair loss
acne mood changes gynecomastia hirsutism liver dysfunction (rare) |
| gptkbp:synonym |
3β-hydroxyandrost-5-en-17-one
prasterone androstenolone |
| gptkbp:usedFor |
gptkb:depression
gptkb:bone dietary supplement adrenal insufficiency anti-aging improving libido |
| gptkbp:bfsParent |
gptkb:androstenedione
|
| gptkbp:bfsLayer |
7
|