|
gptkbp:instanceOf
|
hormone
endogenous compound
|
|
gptkbp:biosynthesized_from
|
cholesterol
|
|
gptkbp:CASNumber
|
145-13-1
|
|
gptkbp:category
|
hormones
neurosteroids
cholestanes
pregnanes
|
|
gptkbp:chemicalFormula
|
C21H32O2
|
|
gptkbp:discoveredBy
|
gptkb:Adolf_Butenandt
gptkb:Edward_Adelbert_Doisy
1934
|
|
gptkbp:effect
|
modulates GABA_A receptor
modulates NMDA receptor
modulates sigma receptor
|
|
gptkbp:foundIn
|
gptkb:adrenal_gland
brain
liver
gonads
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
pregnenolone
|
|
gptkbp:IUPACName
|
3β-hydroxypregn-5-en-20-one
|
|
gptkbp:meltingPoint
|
191–193 °C
|
|
gptkbp:metabolism
|
gptkb:CYP17A1
gptkb:3β-hydroxysteroid_dehydrogenase
|
|
gptkbp:Molar_mass
|
316.48 g/mol
|
|
gptkbp:predecessor
|
gptkb:progesterone
gptkb:aldosterone
cortisol
testosterone
estrogens
|
|
gptkbp:PubChem_CID
|
8955
|
|
gptkbp:relatedTo
|
gptkb:progesterone
gptkb:pregnanolone
gptkb:pregnenolone_sulfate
|
|
gptkbp:role
|
neurosteroid
hormone precursor
|
|
gptkbp:UNII
|
73R90F7MQ8
|
|
gptkbp:usedFor
|
dietary supplement
|
|
gptkbp:bfsParent
|
gptkb:pregnenolone_sulfate
|
|
gptkbp:bfsLayer
|
7
|