mitochondrial permeability transition pore
GPTKB entity
Statements (19)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
calcium overload
|
| gptkbp:associatedWith |
apoptosis
cell death necrosis |
| gptkbp:component |
mitochondrion
adenine nucleotide translocator cyclophilin D voltage-dependent anion channel |
| gptkbp:discoveredIn |
1970s
|
| gptkbp:function |
regulates mitochondrial membrane permeability
|
| https://www.w3.org/2000/01/rdf-schema#label |
mitochondrial permeability transition pore
|
| gptkbp:inhibitedBy |
cyclosporin A
|
| gptkbp:locatedIn |
mitochondrial inner membrane
|
| gptkbp:role |
gptkb:ischemia-reperfusion_injury
mitochondrial swelling |
| gptkbp:bfsParent |
gptkb:SIRT3
gptkb:SLC25A5 |
| gptkbp:bfsLayer |
8
|