Goodpasture syndrome

GPTKB entity

Statements (36)
Predicate Object
gptkbp:instanceOf autoimmune disease
rare disease
gptkbp:affects lungs
kidneys
gptkbp:ageGroupAffected older adults
young adult males
gptkbp:alsoKnownAs anti-glomerular basement membrane disease
gptkbp:cause pulmonary hemorrhage
rapidly progressive glomerulonephritis
gptkbp:characterizedBy autoantibodies against glomerular basement membrane
gptkbp:diagnosedBy gptkb:chest_X-ray
anti-GBM antibody test
kidney biopsy
gptkbp:firstDescribed 1919
Ernest Goodpasture
https://www.w3.org/2000/01/rdf-schema#label Goodpasture syndrome
gptkbp:ICD-10_code M31.0
gptkbp:MeSH_ID D006073
gptkbp:OMIM 233450
gptkbp:prevalence rare
gptkbp:riskFactor smoking
respiratory infections
exposure to hydrocarbons
gptkbp:symptom cough
shortness of breath
hematuria
proteinuria
hemoptysis
gptkbp:treatment corticosteroids
plasmapheresis
immunosuppressive drugs
gptkbp:bfsParent gptkb:Ernest_W._Goodpasture
gptkb:Benjamin_Franklin_Goodpasture
gptkb:Type_IV_collagen
gptkb:collagen_IV
gptkbp:bfsLayer 7