|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
produces multiple isoforms
|
|
gptkbp:associatedWith
|
gptkb:Knobloch_syndrome
|
|
gptkbp:discoveredIn
|
1994
|
|
gptkbp:domain
|
frizzled domain
collagenous domain
endostatin domain
|
|
gptkbp:encodedBy
|
COL18A1 gene
|
|
gptkbp:foundIn
|
basement membrane
|
|
gptkbp:function
|
structural support
angiogenesis regulation
|
|
gptkbp:HGNC_ID
|
2186
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
collagen XVIII
|
|
gptkbp:inhibitedBy
|
angiogenesis (via endostatin)
|
|
gptkbp:locatedOnChromosome
|
chromosome 21q22.3
|
|
gptkbp:molecularWeight
|
~150 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Knobloch_syndrome
|
|
gptkbp:OMIM
|
120328
|
|
gptkbp:predecessor
|
endostatin
|
|
gptkbp:presentIn
|
gptkb:fallopian_tube
gptkb:gallbladder
gptkb:thyroid
gptkb:cancer
gptkb:skin
gptkb:pituitary_gland
gptkb:skeletal_muscle
gptkb:adrenal_gland
gptkb:kidney
gptkb:placenta
gptkb:prostate
gptkb:small_intestine
gptkb:testis
gptkb:thymus
brain
eye
heart
retina
liver
collagen
spleen
tonsil
cornea
lens
optic nerve
bladder
bone marrow
colon
esophagus
lymph node
pancreas
parathyroid gland
salivary gland
stomach
uterus
|
|
gptkbp:species
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:UniProtID
|
P39060
|
|
gptkbp:bfsParent
|
gptkb:heparan_sulfate_proteoglycans
|
|
gptkbp:bfsLayer
|
7
|