clear cell renal carcinoma

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:cancer gptkb:renal_cell_carcinoma
gptkbp:affects	gptkb:kidney
gptkbp:alsoKnownAs	gptkb:ccRCC
gptkbp:associatedWith	gptkb:VHL_gene_mutation
gptkbp:canBeSporadic	yes
gptkbp:canMetastasizeTo	brain lungs liver bones
gptkbp:commonIn	males
gptkbp:diagnosedBy	imaging biopsy
gptkbp:firstDescribed	1883 Paul Grawitz
gptkbp:hasGeneticAlteration	chromosome 3p deletion
gptkbp:hereditary	yes
gptkbp:hereditarySyndrome	gptkb:von_Hippel-Lindau_disease
gptkbp:histology	clear cytoplasm delicate vasculature
gptkbp:ICD-10_code	gptkb:C64
gptkbp:immunohistochemistryMarker	gptkb:CD10 gptkb:CAIX gptkb:PAX8 gptkb:vimentin
gptkbp:mostCommonTypeOf	gptkb:renal_cell_carcinoma
gptkbp:originatedIn	renal tubular epithelial cells
gptkbp:paraneoplasticSyndrome	gptkb:hypercalcemia gptkb:Stauffer_syndrome hypertension polycythemia
gptkbp:peakIncidenceAge	60-70 years
gptkbp:prognosis	gptkb:theatre gptkb:grade metastasis
gptkbp:riskFactor	family history obesity smoking hypertension chronic kidney disease
gptkbp:symptom	hematuria abdominal mass flank pain
gptkbp:treatment	gptkb:radiation_therapy gptkb:immunotherapy gptkb:targeted_therapy surgery
gptkbp:bfsParent	gptkb:Von_Hippel-Lindau_Disease
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	clear cell renal carcinoma