Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
cancer progression
epithelial-mesenchymal transition |
| gptkbp:compatibleWith |
epithelial cells (normally)
|
| gptkbp:component |
intermediate filaments
|
| gptkbp:discoveredIn |
1970s
|
| gptkbp:encodedBy |
VIM gene
|
| gptkbp:expressedIn |
gptkb:leukocytes
macrophages endothelial cells fibroblasts mesenchymal cells |
| gptkbp:foundIn |
humans
vertebrates |
| gptkbp:function |
involved in wound healing
involved in cell migration maintains cell integrity supports cellular organelles |
| https://www.w3.org/2000/01/rdf-schema#label |
vimentin
|
| gptkbp:locatedOnChromosome |
10p13
|
| gptkbp:marking |
gptkb:rhabdomyosarcoma
gptkb:angiosarcoma synovial sarcoma osteosarcoma liposarcoma renal cell carcinoma leiomyosarcoma sarcomas malignant peripheral nerve sheath tumors gliomas lymphomas malignant fibrous histiocytoma schwannomas Kaposi sarcoma astrocytomas endothelial tumors melanomas mesenchymal origin mesotheliomas neuroblastomas |
| gptkbp:molecularWeight |
~54 kDa
|
| gptkbp:PDB |
3TRT
|
| gptkbp:postTranslationalModification |
phosphorylation
glycosylation ubiquitination |
| gptkbp:structure |
coiled-coil protein
|
| gptkbp:UniProtID |
P08670
|
| gptkbp:usedIn |
immunohistochemistry
|
| gptkbp:bfsParent |
gptkb:Cytoskeleton
gptkb:HSC-3 gptkb:UB87 |
| gptkbp:bfsLayer |
7
|