Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
cancer progression
epithelial-mesenchymal transition |
| gptkbp:compatibleWith |
epithelial cells (normally)
|
| gptkbp:component |
intermediate filaments
|
| gptkbp:discoveredIn |
1970s
|
| gptkbp:encodedBy |
VIM gene
|
| gptkbp:expressedIn |
gptkb:leukocytes
macrophages endothelial cells fibroblasts mesenchymal cells |
| gptkbp:foundIn |
humans
vertebrates |
| gptkbp:function |
involved in wound healing
involved in cell migration maintains cell integrity supports cellular organelles |
| gptkbp:locatedOnChromosome |
10p13
|
| gptkbp:marking |
gptkb:renal_cell_carcinoma
gptkb:rhabdomyosarcoma gptkb:angiosarcoma synovial sarcoma osteosarcoma liposarcoma leiomyosarcoma sarcomas malignant peripheral nerve sheath tumors gliomas lymphomas malignant fibrous histiocytoma schwannomas Kaposi sarcoma astrocytomas endothelial tumors melanomas mesenchymal origin mesotheliomas neuroblastomas |
| gptkbp:molecularWeight |
~54 kDa
|
| gptkbp:PDB |
3TRT
|
| gptkbp:postTranslationalModification |
phosphorylation
glycosylation ubiquitination |
| gptkbp:structure |
coiled-coil protein
|
| gptkbp:UniProtID |
P08670
|
| gptkbp:usedIn |
immunohistochemistry
|
| gptkbp:bfsParent |
gptkb:Cytoskeleton
gptkb:HSC-3 gptkb:UB87 |
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
vimentin
|