cerivastatin

URI: https://gptkb.org/entity/cerivastatin

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:hypolipidemic_agent gptkb:statin
gptkbp:approvedBy	1997
gptkbp:ATCCode	gptkb:C10AA06
gptkbp:brand	Baycol Lipobay
gptkbp:CASNumber	145599-86-6
gptkbp:category	gptkb:cholesterol-lowering_agent withdrawn drug
gptkbp:chemicalFormula	C26H34FNO5
gptkbp:contraindication	gptkb:liver_disease pregnancy breastfeeding
gptkbp:developedBy	gptkb:Bayer_AG
gptkbp:discoveredIn	1990s
gptkbp:drugClass	gptkb:statin
gptkbp:eliminationHalfLife	2-3 hours
gptkbp:has_stereochemistry	(3R,5S)
gptkbp:interactsWith	gptkb:cyclosporine gptkb:gemfibrozil gptkb:fibrates gptkb:erythromycin gptkb:ketoconazole niacin itraconazole
gptkbp:IUPACName	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2,6-dimethyl-5-(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoic acid
gptkbp:legalStatus	withdrawn
gptkbp:mechanismOfAction	HMG-CoA reductase inhibitor
gptkbp:MeSH_ID	C098727
gptkbp:metabolism	gptkb:CYP2C8 gptkb:CYP3A4
gptkbp:molecularWeight	451.55 g/mol
gptkbp:pregnancyCategory	gptkb:X_(US)
gptkbp:PubChem_CID	60854 CHEMBL1201212
gptkbp:retired	rhabdomyolysis risk
gptkbp:routeOfAdministration	oral
gptkbp:sideEffect	gptkb:muscular_dystrophy rhabdomyolysis
gptkbp:UNII	N9YNS0M02X
gptkbp:usedFor	lowering cholesterol
gptkbp:withdrawn	2001
gptkbp:bfsParent	gptkb:CYP2C8
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	cerivastatin