Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:class_of_medications
|
| gptkbp:contraindication |
severe liver disease
severe renal disease |
| gptkbp:discoveredIn |
1960s
|
| gptkbp:drugInteraction |
statins
oral anticoagulants |
| gptkbp:effect |
increase HDL cholesterol
lower triglyceride levels modestly lower LDL cholesterol |
| gptkbp:example |
gptkb:gemfibrozil
gptkb:bezafibrate gptkb:ciprofibrate fenofibrate |
| gptkbp:excretion |
kidneys
|
| gptkbp:mechanismOfAction |
activate peroxisome proliferator-activated receptor alpha (PPARĪ±)
|
| gptkbp:metabolism |
liver
|
| gptkbp:pregnancyCategory |
C (varies by country and agent)
|
| gptkbp:regulates |
prescription only
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
gptkb:muscular_dystrophy
liver dysfunction gallstones |
| gptkbp:usedFor |
treatment of hypertriglyceridemia
treatment of hyperlipidemia |
| gptkbp:bfsParent |
gptkb:type_III_hyperlipoproteinemia
gptkb:APOA1 |
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
fibrates
|