|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:VIP21
gptkb:CAV1
|
|
gptkbp:associatedWith
|
lipid rafts
|
|
gptkbp:discoveredBy
|
Rothberg et al.
|
|
gptkbp:discoveredIn
|
1992
|
|
gptkbp:encodedBy
|
CAV1 gene
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000105974
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:skeletal_muscle
gptkb:kidney
gptkb:prostate
heart
liver
colon
pancreas
endothelial cells
fibroblasts
muscle cells
adipocytes
breast tissue
|
|
gptkbp:foundIn
|
gptkb:plasma_membrane
caveolae
|
|
gptkbp:function
|
cholesterol homeostasis
scaffolding protein
regulation of signal transduction
|
|
gptkbp:gene
|
gptkb:CAV1
|
|
gptkbp:HGNC_ID
|
1527
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
caveolin-1
|
|
gptkbp:interactsWith
|
gptkb:Src_family_kinases
gptkb:endothelial_nitric_oxide_synthase
G-protein coupled receptors
|
|
gptkbp:involves
|
tumor suppression
endocytosis
fibrosis
vesicular transport
|
|
gptkbp:locatedOnChromosome
|
7q31.2
|
|
gptkbp:molecularWeight
|
21 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:congenital_generalized_lipodystrophy
pulmonary arterial hypertension
|
|
gptkbp:OMIM
|
601047
|
|
gptkbp:PDB
|
1U7F
|
|
gptkbp:phosphorylates
|
tyrosine 14
|
|
gptkbp:regulates
|
apoptosis
cell proliferation
cell migration
EGFR signaling
insulin signaling
TGF-beta signaling
|
|
gptkbp:UniProtID
|
Q03135
|
|
gptkbp:bfsParent
|
gptkb:SDPR_gene
gptkb:eNOS
|
|
gptkbp:bfsLayer
|
7
|