cadherin 13

GPTKB entity

Statements (45)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:H-cadherin
gptkb:T-cadherin
CDH13
gptkbp:associatedWith gptkb:cancer
gptkb:cardiovascular_disease
attention deficit hyperactivity disorder (ADHD)
gptkbp:biologicalProcess neural development
tumor suppression
vascular development
cell-cell adhesion
gptkbp:cellularComponent gptkb:plasma_membrane
cell surface
gptkbp:downregulatedIn various cancers
gptkbp:encodedBy CDH13 gene
gptkbp:Entrez_Gene_ID 1012
gptkbp:excludes transmembrane domain
gptkbp:expressedIn gptkb:nervous_system
heart
endothelial cells
gptkbp:firstDescribed 1997
gptkbp:function signal transduction
tumor suppression
cell adhesion
gptkbp:geneType protein-coding
gptkbp:HGNC_ID 1740
https://www.w3.org/2000/01/rdf-schema#label cadherin 13
gptkbp:interactsWith gptkb:adiponectin
gptkb:low-density_lipoprotein_(LDL)
gptkbp:locatedOnChromosome chromosome 16q24
gptkbp:memberOf gptkb:cadherin_superfamily
gptkbp:methylationStatus hypermethylated in some tumors
gptkbp:molecularWeight ~78 kDa
gptkbp:OMIM 601364
gptkbp:orthologInMouse gptkb:Cdh13
gptkbp:postTranslationalModification glycosylation
GPI-anchor addition
gptkbp:regulates apoptosis
cell proliferation
cell migration
gptkbp:species gptkb:Homo_sapiens
gptkbp:structure glycosylphosphatidylinositol (GPI)-anchored protein
gptkbp:UniProtID P55290
gptkbp:bfsParent gptkb:MGI:1918920
gptkbp:bfsLayer 7