|
gptkbp:instanceOf
|
gptkb:drug
gptkb:Corticosteroid
|
|
gptkbp:approvedBy
|
1981
|
|
gptkbp:ATCCode
|
gptkb:R01AD05
R03BA02
A07EA06
|
|
gptkbp:bioavailability
|
11% (oral)
9-21% (inhaled)
|
|
gptkbp:brand
|
gptkb:Pulmicort
gptkb:Entocort
gptkb:Rhinocort
|
|
gptkbp:CASNumber
|
51333-22-3
|
|
gptkbp:contraindication
|
hypersensitivity to budesonide
|
|
gptkbp:developedBy
|
gptkb:AstraZeneca
|
|
gptkbp:eliminationHalfLife
|
2-3.6 hours
|
|
gptkbp:excretion
|
urine
feces
|
|
gptkbp:hasMolecularFormula
|
C25H34O6
|
|
gptkbp:IUPACName
|
gptkb:(RS)-11β,21-dihydroxy-16α,17-(butylidenebis(oxy))-pregna-1,4-diene-3,20-dione
|
|
gptkbp:KEGGID
|
D00219
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
glucocorticoid receptor agonist
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
430.53 g/mol
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:proteinBinding
|
85-90%
|
|
gptkbp:PubChem_CID
|
CHEMBL1433
4445532
5280725
DB01222
|
|
gptkbp:routeOfAdministration
|
oral
inhalation
rectal
nasal
|
|
gptkbp:sideEffect
|
nausea
headache
cough
oral thrush
respiratory infections
hoarseness
|
|
gptkbp:UNII
|
Q3OKS62Q6X
|
|
gptkbp:usedFor
|
gptkb:Crohn's_disease
asthma
ulcerative colitis
chronic obstructive pulmonary disease
allergic rhinitis
eosinophilic esophagitis
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
yes
|
|
gptkbp:bfsParent
|
gptkb:Pulmicort
gptkb:CYP3A4
gptkb:Symbicort
gptkb:Easyhaler
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
budesonide
|