Statements (54)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:drug
|
| gptkbp:bfsLayer |
5
|
| gptkbp:bfsParent |
gptkb:Astra_Zeneca_Group
gptkb:budesonide |
| gptkbp:approves |
gptkb:legislation
gptkb:1987 gptkb:United_States |
| gptkbp:brand |
gptkb:Pulmicort
Pulmicort Respules Pulmicort Turbuhaler |
| gptkbp:clinical_trial |
Phase III
long-term management rescue therapy preventive therapy |
| gptkbp:contraindication |
active tuberculosis
hypersensitivity to budesonide |
| gptkbp:dosage_form |
inhalation suspension
|
| gptkbp:excretion |
urine
|
| gptkbp:formulation |
dry powder inhaler
inhalation aerosol |
| https://www.w3.org/2000/01/rdf-schema#label |
Pulmicort
|
| gptkbp:indication |
acute exacerbations
maintenance treatment |
| gptkbp:ingredients |
gptkb:budesonide
|
| gptkbp:interacts_with |
CY P3 A4 inducers
CY P3 A4 inhibitors |
| gptkbp:is_atype_of |
R03 B A02
|
| gptkbp:is_involved_in |
gptkb:Person
adults |
| gptkbp:is_used_for |
gptkb:asthma
chronic obstructive pulmonary disease |
| gptkbp:legal_issue |
prescription only
|
| gptkbp:lifespan |
2.5 hours
|
| gptkbp:manager |
inhalation
|
| gptkbp:manufacturer |
gptkb:temple
|
| gptkbp:marketed_as |
Pulmicort Flexhaler
Pulmicort Respules |
| gptkbp:packaging |
blister pack
pressurized canister |
| gptkbp:pharmacokinetics |
metabolized in liver
glucocorticoid receptor agonist |
| gptkbp:safety_features |
generally well tolerated
|
| gptkbp:side_effect |
gptkb:sneaker
headache cough nasal congestion cataracts osteoporosis throat irritation oral thrush adrenal suppression growth suppression in children |
| gptkbp:social_structure |
C25 H34 O6 S
|
| gptkbp:storage |
room temperature
|