Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:Hex_A
gptkb:N-acetyl-beta-hexosaminidase_A |
| gptkbp:associatedWith |
gptkb:Sandhoff_disease
|
| gptkbp:biologicalProcess |
glycosidase activity
|
| gptkbp:CASNumber |
37278-88-3
|
| gptkbp:catalyzes |
hydrolysis of GM2 ganglioside
|
| gptkbp:deficiencyCauses |
gptkb:Tay-Sachs_disease
|
| gptkbp:EC_number |
3.2.1.52
|
| gptkbp:encodedBy |
gptkb:HEXA_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
other mammals |
| gptkbp:GO_term |
GO:0004563
|
| gptkbp:locatedOnChromosome |
15q23-q24
|
| gptkbp:location |
gptkb:lysosome
|
| gptkbp:OMIM |
606869
|
| gptkbp:structure |
heterodimer
|
| gptkbp:substrate |
gptkb:GM2_ganglioside
glycosaminoglycans glycolipids glycoproteins |
| gptkbp:subunit |
alpha subunit
beta subunit |
| gptkbp:UniProtID |
P06865
|
| gptkbp:bfsParent |
gptkb:GM2_ganglioside
|
| gptkbp:bfsLayer |
8
|
| http://www.w3.org/2000/01/rdf-schema#label |
beta-hexosaminidase A
|