|
gptkbp:instance_of
|
gptkb:pharmaceuticals
|
|
gptkbp:administered_by
|
injection
oral tablet
|
|
gptkbp:affects
|
DNA synthesis
immune system
|
|
gptkbp:approves
|
gptkb:FDA
|
|
gptkbp:available_on
|
generic drug
|
|
gptkbp:brand
|
Imuran
|
|
gptkbp:chemical_formula
|
C7 H10 N4 O3 S
|
|
gptkbp:contraindication
|
pregnancy
active infections
|
|
gptkbp:discovered_by
|
1960s
|
|
gptkbp:dosage_form
|
gptkb:tablet
injection
1-3 mg/kg/day
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
azathioprine
|
|
gptkbp:interacts_with
|
gptkb:ACE_inhibitors
gptkb:warfarin
allopurinol
|
|
gptkbp:is_monitored_by
|
liver function tests
complete blood count
|
|
gptkbp:mechanism_of_action
|
gptkb:immunotherapy
|
|
gptkbp:metabolism
|
thiopurine methyltransferase
|
|
gptkbp:related_to
|
gptkb:mercaptopurine
6-thioguanine
|
|
gptkbp:research
|
gptkb:cancer_treatment
gptkb:myasthenia_gravis
gptkb:multiple_sclerosis
gptkb:Open_VMS
gptkb:dermatomyositis
psoriasis
transplant rejection prevention
|
|
gptkbp:safety
|
gptkb:D
|
|
gptkbp:side_effect
|
nausea
vomiting
liver toxicity
bone marrow suppression
|
|
gptkbp:storage
|
room temperature
|
|
gptkbp:symptoms
|
gptkb:none
|
|
gptkbp:treatment
|
severe Crohn's disease
severe ulcerative colitis
severe rheumatoid arthritis
|
|
gptkbp:used_for
|
organ transplantation
autoimmune diseases
|
|
gptkbp:used_in
|
gptkb:Crohn's_disease
gptkb:ulcerative_colitis
gptkb:Canis_lupus
gptkb:rheumatoid_arthritis
|
|
gptkbp:bfsParent
|
gptkb:granulomatosis_with_polyangiitis
gptkb:lambert-eaton_syndrome
gptkb:Lialda
gptkb:ribavirin
|
|
gptkbp:bfsLayer
|
6
|