Statements (57)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:pharmaceuticals
|
| gptkbp:administered_by |
intravenous infusion
oral tablets |
| gptkbp:affects |
blood pressure
cardiac output renal blood flow |
| gptkbp:approves |
gptkb:FDA
|
| gptkbp:available_in |
generic form
brand name form |
| gptkbp:can_be_combined_with |
beta-blockers
statins calcium channel blockers |
| gptkbp:can_be_used_in |
gptkb:diabetes
chronic kidney disease heart attack recovery left ventricular dysfunction post-stroke management prevention of heart failure systolic heart failure |
| gptkbp:can_cause |
angioedema
first-dose hypotension |
| gptkbp:class |
antihypertensive drugs
|
| gptkbp:contraindication |
pregnancy
renal artery stenosis |
| gptkbp:developed_by |
gptkb:scientists
|
| gptkbp:discovered_by |
1970s
|
| gptkbp:example |
gptkb:Enalapril
gptkb:Lisinopril gptkb:Ramipril |
| https://www.w3.org/2000/01/rdf-schema#label |
ACE inhibitors
|
| gptkbp:increased |
bradykinin levels
|
| gptkbp:interacts_with |
NSAIDs
lithium diuretics |
| gptkbp:is_effective_against |
isolated systolic hypertension in elderly
|
| gptkbp:is_monitored_by |
electrolytes
renal function |
| gptkbp:is_recommended_for |
diabetic nephropathy
post-myocardial infarction |
| gptkbp:mechanism_of_action |
inhibit angiotensin-converting enzyme
|
| gptkbp:reduces |
risk of stroke
mortality in heart failure risk of myocardial infarction |
| gptkbp:side_effect |
cough
hypotension hyperkalemia |
| gptkbp:suitable_for |
severe renal impairment
patients with history of angioedema |
| gptkbp:treatment |
hypertension
heart failure |
| gptkbp:used_for |
hypertension
heart failure |
| gptkbp:bfsParent |
gptkb:Basaglar
gptkb:Rapid-acting_insulin gptkb:Ibuprofen gptkb:Levemir |
| gptkbp:bfsLayer |
5
|