|
gptkbp:instance_of
|
gptkb:disease
|
|
gptkbp:affects
|
gptkb:Skin
kidneys
lungs
joints
blood vessels
eyes
upper respiratory tract
|
|
gptkbp:associated_with
|
ANCA antibodies
|
|
gptkbp:autoimmune
|
gptkb:true
|
|
gptkbp:cause
|
gptkb:multiple_sclerosis
inflammation
|
|
gptkbp:complication
|
hearing loss
lung damage
skin lesions
nerve damage
kidney failure
|
|
gptkbp:condition
|
gptkb:microscopic_polyangiitis
gptkb:Churg-Strauss_syndrome
gptkb:Wegener's_granulomatosis
|
|
gptkbp:diagnosis
|
CT scan
variable
blood tests
biopsy
depends on severity
depends on treatment
|
|
gptkbp:first_described_by
|
1950s
|
|
gptkbp:gender
|
more common in males
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
granulomatosis with polyangiitis
|
|
gptkbp:inflammatory
|
gptkb:true
|
|
gptkbp:is_monitored_by
|
regular follow-ups
lung function tests
kidney function tests
ANCA levels
|
|
gptkbp:named_after
|
gptkb:Friedrich_Wegener
|
|
gptkbp:premiered_on
|
adulthood
|
|
gptkbp:prevalence
|
rare
|
|
gptkbp:research
|
ongoing
|
|
gptkbp:risk_factor
|
smoking
genetic predisposition
infections
environmental exposures
|
|
gptkbp:scientific_classification
|
small vessel vasculitis
|
|
gptkbp:symptoms
|
fatigue
cough
sinusitis
hematuria
|
|
gptkbp:treatment
|
gptkb:methotrexate
gptkb:cyclophosphamide
gptkb:rituximab
gptkb:azathioprine
corticosteroids
plasma exchange
immunosuppressants
|
|
gptkbp:bfsParent
|
gptkb:Rituximab
gptkb:Rituxan
|
|
gptkbp:bfsLayer
|
5
|