granulomatosis with polyangiitis

GPTKB entity

Statements (49)
Predicate Object
gptkbp:instanceOf autoimmune disease
vasculitis
gptkbp:affects gptkb:skin
lungs
kidneys
eyes
joints
medium blood vessels
small blood vessels
upper respiratory tract
gptkbp:alsoKnownAs gptkb:Wegener's_granulomatosis
gptkbp:associatedWith gptkb:antineutrophil_cytoplasmic_antibodies
gptkbp:complication gptkb:chronic_sinusitis
gptkb:subglottic_stenosis
renal failure
skin ulcers
arthritis
hearing loss
vision loss
peripheral neuropathy
pulmonary hemorrhage
saddle nose deformity
gptkbp:diagnosedBy imaging
blood test
biopsy
gptkbp:field nephrology
rheumatology
pulmonology
gptkbp:firstDescribed gptkb:Friedrich_Wegener
https://www.w3.org/2000/01/rdf-schema#label granulomatosis with polyangiitis
gptkbp:ICD-10_code gptkb:M31.3
gptkbp:mortalityRate high if untreated
gptkbp:prevalence rare
gptkbp:prognosis improved with treatment
gptkbp:riskFactor genetic predisposition
environmental factors
gptkbp:symptom gptkb:sinusitis
fever
weight loss
cough
hematuria
hemoptysis
nasal congestion
gptkbp:treatment gptkb:cyclophosphamide
gptkb:rituximab
corticosteroids
immunosuppressants
gptkbp:bfsParent gptkb:Heinrich_Hertz
gptkbp:bfsLayer 4